FNAIT Maternal Evaluation
Test Description
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare condition where the mother's immune system identifies the baby's platelets as foreign and elicits an immune response leading to the destruction of the baby's platelets. It results from maternal alloimmunization to fetal human platelet antigens (HPA) inherited from the father. This assay is used for the initial screening of FNAIT when a paternal sample is not available for testing.
Test Type
platelet surface immunofluorescence test (PSIFT)
Additional Test Name(s)
Fetal and neonatal alloimmune thrombocytopenia investigation, neonatal alloimmune thrombocytopenia workup.
Sample Notes
Whole blood (EDTA) from lavender or pink top tube. Do not spin or separate.
Requested Volume
Sample volume requirements are based on platelet count
Shipping Information
Store and ship at room temperature. Samples must be received in the testing lab within 48 hours of collection.
Method
Fluorescense Microscopy and Manual Interpretation
Turnaround Time
7-10 days
Accepts NY State Samples
Yes
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National Reference Laboratory for Specialized Testing
Email
NRLST_staff@redcross.org
Phone
(215) 451-4205
Fax
(215) 351-0179